Learned by Reading
In Wikipedia:
Mutations in the CARD15 gene (also known as the NOD2 gene) are associated with Crohn’s disease and with susceptibility to certain phenotypes of disease location and activity.
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In the ICWSM 2009 Weblog Corpus:
Delinquency for example among western youth is a real problem, not because of a bizarre mutation in a gene expressed during adolescence, but because the society that these youth have grown into has failed them.
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In the ICWSM 2009 Weblog Corpus:
A mutation in one gene, osm – 9 (n2473), causes defects in both touch avoidance and osmotic avoidance.
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In the ICWSM 2009 Weblog Corpus:
Hydrolethalus syndrome is inherited in an autosomal recessive manner and is caused by a missense mutation in the HYLS gene.
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In the ICWSM 2009 Weblog Corpus:
Synthetic enhancement of phenotypes resulting from a defined mutation in a miRNA gene in combination with knockdown of a library gene will indicate a genetic interaction between these two genes.
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In the ICWSM 2009 Weblog Corpus:
Mol Cancer. 2008 Aug 21; 7 (1): 68 Brim H, Mokarram P, Naghibalhossaini F, Saberi – Firoozi M, Al – Mandhari M, Al – Mawaly K, Al – Mjeni R, Al – Sayegh A, Raeburn S, Lee E, Giardiello F, Smoot DT, Vilkin A, Boland RC, Goel A, Hafezi M, Nouraie M, Ashktorab H ABSTRACT: We have identified an alternative pathway of tumorigenesis in sporadic colon cancer, involving microsatellite instability due to mismatched repair methylation, which may be driven by mutations in the BRAF gene (V600E).
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In Wikipedia:
Gaucher disease (mutations in the “GBA” gene), Crohns disease (mutation of “NOD2”) and familial hypertrophic cardiomyopathy (mutations in “CMH1”, “CMH2”, “CMH3” and “CMH4”) are all examples of negative selection.
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(. .)))
In Wikipedia:
It should be noted that MPS – III A, B, C and D are considered to be clinically indistinguishable, although mutations in different genes are responsible for each disease.
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In Wikipedia:
Recent genetic studies have revealed a mutation in one gene, “vrs1” is responsible for the transition from two – row to six – row barley Two – row barley has a lower protein content than six – row barley and thus more fermentable sugar content.
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In Wikipedia:
Clinically, most cases of hemochromatosis are found in homozygotes for the most common mutation in the HFE gene.
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In the ICWSM 2009 Weblog Corpus:
Mutations in the human gene encoding tau cause the neurodegenerative disorder, frontotemporal dementia with parkinsonism chromosome 17 type (FTDP – 17), demonstrating that tau defects can cause disease.
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In the ICWSM 2009 Weblog Corpus:
autoimmune polyendocrine syndromes affect more than one endocrine gland, but can also affect non – endocrine organs as well. they are driven by inappropriate MHC – TCR – antigen interactions that encourage the production of aberrant antibody production. here is a summary of how these processes are driven: Type I AIPS also known as candidiasis – hypoparathyroidism – Addison’s disease – syndrome, and autoimmune polyendocrine candidiadis ectodermal dystrophy (APECED). it is an autosomal recessive disorder caused by a mutation in the AutoImmune Regulator AIRe gene. this gene is expressed mainly in the thymus. its protein product is a transcription factor that allows the thymus cells to express tissue – specific genes so that thymus cells can present’ ‘self’’ antigens, normally found outside of the thymus, to maturing T – cells.
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In Wikipedia:
Wiskott – Aldrich syndrome was linked in 1994 to mutations in a gene on the short arm of the X chromosome, which was termed “Wiskott – Aldrich syndrome protein” (“WASP”).
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In Wikipedia:
Mutations in this gene are associated with the French – Canadian type of Leigh syndrome.
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In Wikipedia:
Mutations in the NSD1 gene cause Sotos syndrome.
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In Wikipedia:
The exceptions, people who have mutations in the gene for ferroportin, prove the rule: these people have plenty of hepcidin, but their cells lack the proper response to it.
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In Wikipedia:
CF is caused by a mutation in the gene coding for the “cystic fibrosis transmembrane conductance regulator” (“CFTR”) protein.
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In the ICWSM 2009 Weblog Corpus:
We have isolated a mutation in a previously unidentified gene, pod – 2 (for polarity and osmotic defect), through a screen for cold sensitive embryonic lethals.
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In Wikipedia:
Virtually all patients with the syndrome have mutations in the gene for mevalonate kinase, which is part of the HMG – CoA reductase pathway, an important cellular metabolic pathway.
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(. .)))
And 1,109 more sentences.